DOPO shows lower fish toxicity than legacy FRs
Toxicity to fish embryos was compared between two halogenated legacy FRs (TDCPP, TBBPA) and the next generation PIN FR DOPO (9,10-Dihydro-9-oxa-10-phosphaphenanthrene 10-oxide). DOPO showed lower toxicity to zebra fish embryos (96h) both when single chemicals were tested and when mixtures were tested. The authors conclude that these results suggest that DOPO is a suitable substitute for halogenated FRs.
“Acute mixture toxicity of halogenated chemicals and their next generation counterparts on zebrafish embryos”, A. Godfrey et al., Chemosphere 181 (2017) 710e712 http://dx.doi.org/10.1016/j.chemosphere.2017.04.146