Posted on 06/07/2020 in Fire Safety 2020
Organophosphate esters and birth outcomes

A study of 90 women* found no significant correlation between social and environmental exposure factors (questionnaire) and urinary organophosphate ester (OPE) metabolites. The study conclusions indicate that higher urinary levels of the halogenated ester derivate BDCIPP** were associated to changes in infant birth weight and umbilical cord levels of insulin and leptin (pinfa note: none of these results were statistically significant at the P=5% level). Metabolites of non-halogenated phosphate esters, and one other halogenated metabolite, showed no association to infant outcomes.

* ORigins of Child Health and Resilience in Development (ORCHARD) pregnancy cohort, Baltimore. ** BDCIPP = bis(1,3-dichloro-2-propyl) phosphate
“Predictors and reproducibility of urinary organophosphate ester metabolite concentrations during pregnancy and associations with birth outcomes in an urban population”, J. Kruiper et al., Environmental Health (2020) 19:55

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