A population study of 260 children with pre-school ADHD was compared to a stratified control group of 549, with data of organophosphate metabolites in mother’s urine at 17 weeks pregnancy. Statistically positive significant correlation was found between levels of DnBP (Di-n-butyl phosphate) and BDCIPP (Bis(1,3-dichloro-2-propyl) phosphate), whereas for BBOEP (Bis(2-butoxyethyl) phosphate) the correlation was negative for girls and positive for boys. The study notes that organophosphates are used for different applications, including as plasticisers and flame retardants.
“Gestational organophosphate ester exposure and preschool attention-deficit/hyperactivity disorder in the Norwegian Mother, Father, and Child cohort study”, A. Hall et al., Int. J. Hygiene and Environmental Health 248 (2023) 114078 https://doi.org/10.1016/j.ijheh.2022.114078