The European commission has published the Classification of titanium dioxide (TiO2) as a category 2 suspected carcinogen by inhalation, applicable in GHS from 9th September 2021. Liquid or solid mixtures containing ≥1% titanium dioxide with diameter ≤ 10 µm will have to be labelled Carc.2 H351 with the new warning phrases EUH211 or EUH212 respectively. Titanium dioxide has been shown to be an effective FR synergist, and if immobilised in polymers it is not respirable and not subject to this suspect carcinogen classification.
The new warning phrases: EUH211 “Warning! Hazardous respirable droplets may be formed when sprayed. Do not breathe spray or mist”, EUH212 “Warning! Hazardous respirable dust may be formed when used. Do not breathe dust.”
EU Official Journal publication, 4th October 2019 https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=uriserv:OJ.L_.2020.044.01.0001.01.ENG&toc=OJ:L:2020:044:TOC