Safe and Sustainable-by-Design (SSbD)

Safe and Sustainable-by-Design (SSbD)

For chemicals, the EU emphasises safer plastic additives, product performance, recycling, harmonised approaches. A number of recent European Commission publications and workshops address the objective of “safe and sustainable by design” fixed by the new EU Chemicals...
UK Fire Safety Act 2021

UK Fire Safety Act 2021

New regulation, following the Grenfell catastrophe, extends fire safety obligations but leaves unclear who will pay the costs. Fire Safety Orders for buildings with two or more dwellings will now extend to the structure, walls, doors, windows. The Act also introduces...
Complexity of neurodevelopmental toxicity assessment.

Complexity of neurodevelopmental toxicity assessment.

Fifteen brominated, chlorinated or phosphate ester flame retardants were tested using a battery of 22 different in vitro neurodevelopmental endpoint tests. Only one FR (TCIPP) showed no effect in all tests. The others showed effects in one or several tests, at...
Complexity of neurodevelopmental toxicity assessment.

Degradation products of TPP (TPHP).

Degradation of the phosphate ester FR triphenyl phosphate (generally abbreviated as TPP, here as TPHP) were studied in experiments with green microalgae, invertebrates and fish, at exposure 100 µg/l (below the NOEC). 29 biotransformation products were identified, in...